In a chemical design, Synapse combines groups into candidate molecular structures and then estimates the physical properties of each of these candidates. In a mixture selection, Synapse retrieves or estimates the physical properties of hundreds of mixtures searching for those that satisfy the set of selection constraints. To obtain the required groups, chemicals, mixtures and estimation techniques, every design and selection requires a source knowledge base. This source knowledge base is specified in the Source Knowledge Base Section.
The Knowledge Base Section contains one field used to enter the name of the associated knowledge base.
The Source Knowledge Base Section stores the the full pathname, folder plus filename, of the source knowledge base so it can be opened and accessed during a design or selection. If an absolute pathname is specified, e.g., K:\MyDocuments\Designs\SourceKB.mkskbd, then if you ever move or archive the files to a new location the design or selection will not be able to find the source knowledge base.
Using the "Use Local Pathname" option when selecting the source knowledge base will inform the application to look for the source knowledge base in the same folder as the current design document. Using this option allows you to move the files to any other folder and still be operable.
See documentation on the Open Knowledge Bases Dialog for additional details.
|Getting Started using Synapse
|provides a quick tour of Synapse's capabilities including examples of chemical product design.
|Designing Chemical Products
|a short video demonstrating how to use Synapse to design candidate chemicals that satisfy a set of physical property and molecular structure constraints.